Granulomatous bone marrow involvement of Hodgkin lymphoma, nodular sclerosis type

Granulomatous bone marrow involvement of Hodgkin lymphoma, nodular sclerosis type

Discordant bone marrow involvement in non-Hodgkin lymphoma.

A discordant lymphoma occurs where 2 distinct histologic subtypes coexist in at least 2 separate anatomic sites. Histologic discordance is most commonly observed between the bone marrow (BM) and lymph nodes (LNs), where typically aggressive lymphoma is found in a LN biopsy with indolent lymphoma in a BM biopsy. Although the diagnosis of discordance relied heavily on histopathology alone in the ...

GWAS Analysis of Young Adult Nodular Sclerosis Hodgkin Lymphoma

Rationale General Background NSHL is the most common subtype of Hodgkin lymphoma in young adults, comprising between 60-80% of the disease in this age group; it occurs equally in males and females, peaks in incidence in the early 20’s, and is associated with higher socioeconomic status and low prevalence of Epstein-Barr virus in the tumors (1,2). Although commonly classified together with the m...

Nodular sclerosis Hodgkin lymphoma with classic Reed-Sternberg cells.

A 15-year-old young man presented to the emergency department with a 3-week history of sharp left-sided chest pain, shortness of breath on exertion, and a low-grade intermittent fever. Chest radiograph revealed increased density in the upper left lobe, thus he was treated with antibiotics for query pneumonia. Although his fever subsided, the patient continued to have chest pain, and subsequentl...

Frequency And Pattern Of Bone Marrow Involvement Among Patients With Non Hodgkin Lymphoma.

BACKGROUND Non-Hodgkin lymphoma (NHLs) are a heterogeneous group of lymphoid neoplasms, characterized by an irregular pattern of spread and may present with extranodal involvement This study was conducted to determine the frequency and pattern of Bone marrow involvement on trephine biopsy in cases of Non-Hodgkin lymphoma (NHL). METHODS This cross sectional study was conducted in Pathology dep...